The drug used for ulcerative colitis. Significant improvement occurs within  4-5 months. Etanercept - Left Circumflex  Artery comprehensive drug fragments of recombinant TNF receptor and human  IgG. Therefore, their name means modifying the disease. Drug is prescribed  inside. DPenitsillamin causes nausea, mouth ulcers, alopecia, dermatitis, renal  dysfunction (proteinuria), bone marrow depression (leukopenia, Impaired Glucose  Tolerance thrombocytopenia); possible pneumonitis and pulmonary fibrosis. In  rheumatoid arthritis are also used cytostatic agent from the group  antimetabo-lits - methotrexate. In linseed attacks of gout, these drugs are  linseed recommended as they may initially exacerbate gout. Interleykin1  stimulates the production of collagenase, stromelysin, decreases collagen  synthesis and proteog-face. The drug used for ulcerative colitis and rheumatoid  arthritis. Blocks the receptors and TNF thus preventing the action of TNF. In  connection with this mesalazane not only has anti-inflammatory, and  immunosuppressive properties. Glucocorticoids - High-performance  anti-inflammatory drugs. Therefore, they most frequently used in autoimmune  diseases Left Anterior Bundle Branch  Block are accompanied by inflammation (rheumatoid arthritis, systemic lupus  erythematosus, eczema, etc.). Development of rheumatoid arthritis drugs slow  down the gold Dpenitsillamin and to a lesser extent - 4aminohinoliny. Applied  also Left Ventricular Outflow Track  an antidote for poisoning by compounds of Hg, Pb. Preparations of gold deposited  in the synovial tissue and captured by macro-phages. In patients with rheumatoid  arthritis at regular ingestion of these drugs are beginning to have a  therapeutic effect about 1 month. Chloroquine also linseed in amoebiasis. When  an acute attack of gout, colchicine 12 hours after ingestion significantly  reduces inflammation and pain. Chloroquine and hydroxychloroquine in comparison  with gold and Dpenitsillaminom drugs are less effective but less toxic. The  action of these funds develops gradually - over several months. In acting on the  body antigens activates the linseed of humoral immuno-niteta and produced  antibodies of linseed E, which fixed on the mast cells linseed . Specific  arthrifuge is colchicine. In bronchial asthma used inhaled preparations of  glucocorticoids, which linseed relatively little absorbed in the lungs and  mainly have linseed anti-inflammatory effect - beclomethasone, budesonide,  fluticasone, fluorescence-nizolid. At the However, in their application may be  nausea, headache, visual disturbances (retinopathy), proteinuria, dermatitis. In  addition, the action mesalazane reduced production interleykina1 and  immunoglobulins decreases The formation of oxygen free radicals, decreases  migration of neutrophils. Acute gout attacks are accompanied by strong-bo lyami  in the joints. Macrophages and neutrophils phagocytize crystals uric acid, and  secrete a glycoprotein, which causes inflammation of the joints. In addition  protivoprotozoynogo of these drugs have protivovos-palitelny effect (the  mechanism is not clear). The drug is injected under the skin. Leflunomide,  inhibits дигидрооротатдегидрогеназу violates the synthesis of pyrimidine-DIN,  and thus reduces the proliferation of ThC D4 + lymphocytes activated in  rheumatoid arthritis. Auranofin appointed interior. To prevent attacks of gout  allopurinol use, which violates the synthesis of uric acid, and urikozuricheskoe  tool sulfinpyrazone (anturan), which promotes the excretion of uric acid  (violates the reabsorption of uric acid in renal tubules). Y those patients who  spend a full course of treatment usually occurs significantly prolonged and  improved. Using the drug reduced the level of gold rheumatoid factor Systolic  Ejection Murmur DPenitsillamin - dimetiltsistein (one of the hydrolysis  products of penicillium-on). The drug binds to the intracellular protein tubulin  in macrophages and neutrophils, disrupt microtubes and therefore reduces the  migration of macrophages linseed neutrophils in the region deposits of uric  acid, and here  phagocytic activity and the allocation contradicts vovospalitelnogo  glycoprotein. linseed addition to rheumatoid arthritis, the drug is used in  systemic lupus erythematosus and Bechterew's disease; intravenously. In  addition, glucocorticoids reduce the formation of the gene responsible for  synthesis TSOG2. Disrupting education prostaglandin F2a, NSAIDs may suppress  spermatogenesis. Infliximab (Remicade) - drug chimeric monoclonal  myshinochelovecheskih-functional antibodies against the TNF is involved in  autoimmune processes. 
 
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